KMID : 1094020180350040141
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Journal of Veterinary Clinics 2018 Volume.35 No. 4 p.141 ~ p.143
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A Case of Nasal Diffuse Large B-Cell Lymphoma in a Cat
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Kim Seong-Jun
Kim Jun-Young Oh Dong-Keun Cho Jun-Ho Park Hee-Myung Kang Min-Hee
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Abstract
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A 6-year-old spayed female Turkish Angora cat presented with sneezing, nasal discharge, and decreasedappetite lasting for 21 days. Skull radiography revealed slightly increased density of soft tissue in the left nasal cavity. Computed tomography (CT) scan revealed an extensive mass with nasal septum destruction and moderate contrastenhancement in the left nasal cavity. After surgical biopsy, histopathological examination confirmed that the mass wasan infiltrative round cell neoplasm, composed of sheets of large neoplastic cells. Immunohistochemical analysis revealedthat most of the neoplastic cells were strongly positive for CD79a and weakly positive for PAX5. Additionally, numerousmature lymphocytes were found to be positive for CD3. This is the first reported case of nasal diffuse large B-celllymphoma (DLBCL) in a Turkish Angora cat in Korea.
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KEYWORD
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nasal tumor, diffuse large B-cell lymphoma (DLBCL), histopathology, immunohistochemistry (IHC), cat
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